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In the management of Total Anomalous Pulmonary Venous Return (TAPVR), providing 100% fractional inspired oxygen (FiO2) through intubation is crucial until surgical intervention can be performed. TAPVR is a congenital heart defect characterized by the pulmonary veins draining into the systemic venous circulation instead of the left atrium, leading to oxygen-poor blood being circulated throughout the body.

Intubation may be necessary to ensure the airway is protected and to provide adequate ventilation. Administering 100% FiO2 helps to maximize oxygen delivery to hypoxic tissues and can significantly improve the oxygenation status of the neonate, which is vital in managing the acute symptoms of this condition. The aim is to stabilize the patient pre-operatively, as surgical correction of TAPVR is the definitive treatment.

Focusing on the reasons other options are not suitable, increasing fluid intake may not specifically address the immediate needs of a patient with TAPVR and could lead to fluid overload. Administering antibiotics may be necessary later in the course of care, especially if infection is suspected, but it does not directly manage the acute respiratory and circulatory issues presented by TAPVR. Monitoring medication compliance is generally more applicable to chronic conditions and is not